With docetaxel for metastatic breast cancer after failure of prior anthracycline-containing regimen. See full labeling. Give cyclically 2 weeks on, 1 week off. Swallow whole. Hepatic or renal impairment. Veterinary regulatory Overview Research and development Marketing authorisation Post-authorisation.
Xeloda RSS. Table of contents Overview Authorisation details Product information Assessment history. Patient safety. Patient safety information. Xeloda is a cancer medicine that is used to treat: colon large bowel cancer. Xeloda is used on its own or with other cancer medicines; advanced gastric stomach cancer. Xeloda is used with other cancer medicines, including a platinum-containing cancer medicine such as cisplatin; locally advanced or metastatic breast cancer breast cancer that has begun to spread to other parts of the body.
Xeloda is used with docetaxel another cancer medicine after treatment with anthracyclines another type of cancer medicine has failed. It can also be used on its own when treatment with both anthracyclines and taxanes another type of cancer medicine has failed or when further treatment with anthracyclines is not suitable for the patient.
Xeloda contains the active substance capecitabine. Expand section Collapse section. Xeloda should only be prescribed by a doctor who is experienced in the use of cancer medicines. Colon cancer In colon cancer, Xeloda on its own has been shown to be as effective as the combination of fluorouracil and folinic acid a medicine that enhances the effects of fluorouracil in a main study involving 1, patients who had had surgery for their cancer.
Colorectal cancer In metastatic colorectal cancer, Xeloda taken on its own was as effective as the combination of fluorouracil and folinic acid in 2 studies involving 1, patients. Gastric cancer In advanced gastric cancer, Xeloda with cisplatin was as effective as a combination of fluorouracil and cisplatin in slowing down the disease in a study involving patients. Breast cancer In locally advanced or metastatic breast cancer, Xeloda with docetaxel was more effective than docetaxel on its own in a study involving women.
Xeloda must also not be used in the following groups: patients who have had severe and unexpected reactions to fluoropyrimidine therapy; patients known to have no DPD enzyme activity; pregnant or breastfeeding women; patients with severe leucopenia, neutropenia, or thrombocytopenia low levels of white cells or platelets in the blood ; patients with severe liver or kidney disease; patients taking brivudine an antiviral medicine for treating shingles or chickenpox or who have taken it in the last 4 weeks.
Xeloda received a marketing authorisation valid throughout the EU on 2 February Authorisation details. Product details Name Xeloda. The patent for capecitabine is set to expire on December 14, The global sales for the agent have continued to rise since its approval. To date, a generic version of the drug has not been made available. Since its initial approval in MBC, capecitabine has become widely utilized in several settings.
You should take it precisely as your doctor has exhorted. Misinterpreting it in or taking an excessive amount of can cause intense incidental effects. The most well-known symptoms of this medication incorporate regurgitating, shortcoming, sickness, stomach agony, and the runs.
This medication may lessen the number of platelets decline white platelets in your blood, subsequently expanding the weakness to contaminations. Custom blood tests are needed to check your platelets alongside heart, liver, and blood uric corrosive levels. For more click here.
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